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. 2021 Mar 31;11:7269. doi: 10.1038/s41598-021-86587-3

Figure 4.

Figure 4

(A,B) Isometric relaxation of thoracic and abdominal aortic rings of EC-EGFR-KO and EC-EGFR-KO under SFD in response to SNAP. (C,D) Isometric relaxation of thoracic and abdominal aortic rings of VSMC-EGFR-KO and VSMC-EGFR-KO under SFD in response to SNAP. Number of animals in the EC-model: N(WT, SFD) = 10, N(KO, SFD) = 8. Number of animals in the VSMC-model: N(WT, SFD) = 10, N(KO, SFD) = 10. *p < 0.05 versus respective control. SFD standard diet, HFD high fat diet, WT wiltype, KO knockout, EC endothelial cell, VSMC vascular smooth muscle cell.