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. 2021 Mar 31;11:7269. doi: 10.1038/s41598-021-86587-3

Figure 5.

Figure 5

Pressure myography in mesenteric arteries of the EC-EGFR model. (A) Contraction in reponse to 20 mmol/l KCl. (B) Contraction in response to 100 nmol/l U46619. (C) Diameter of mesenteric arteries. (D) Wall-to-lumen ratio of mesenteric arteries. (E) Carbachol-induced dilatation. (F) SNAP-induced dilatation. (G) Phenylephrine-induced contraction. Number of animals N(WT, SFD) = 8, N(WT, HFD) = 10, N(KO, SFD) = 10, N(KO, HFD) = 14. *p < 0.05. SFD standard diet, HFD high fat diet, WT wildtype, KO knockout. *p < 0.05. #p < 0.05 versus WT, SFD.