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. 2021 Mar 31;4:436. doi: 10.1038/s42003-021-01962-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a H&E section of skin and subcutaneous fascia with cosmetically injected brown-black tattoo pigment. Pigment particles are present in the papillary and reticular dermis and subcutaneous fascia, visible at low magnification. b, c Higher magnification views of the rectangular areas demonstrate both intracellular particles (within macrophages; long arrows) and extracellular particles (within interstitial spaces; short arrows) of the papillary dermis (b), reticular dermis, and subcutaneous fascia (c). Scale bars = 100 μm.