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. 2021 Mar 18;9:624116. doi: 10.3389/fped.2021.624116

Table 1.

Immunophenotypic evaluation of pediatric subjects.

Subject Subject
Evaluation (units) Normal values for age 12 mo V-1 V-2 Normal values for age 6-8 years V-3 V-4
Age at evaluation 13 months 12 months 6 years 8 years
IgG [mg/dL] 246–904 895
IgA [mg/dL] 27–66 73
IgM [mg/dL] 40–143 56
IgE [IU/mL] 0–200 5.2
Pneumococcal Titers >50% protective 5/10
Diphtheria [IU/mL] ≥0.01 1.83
Tetanus [IU/mL] ≥0.01 2.83
Hib [mg/dL] 1 0.81
WBC [10*3/mm3] 6.4–13.0 9.9 6.14 4.4–9.58 6.73 6.2
Hgb [g/dL] 10–13.2 11.2 10.1 10.9–14.9 13.5 14.8
MCV [fL] 70–90 80 30.3 76–98 78 85
PLT [10*3/mm3] 150–450 214 129 150–450 250 264
ANC [cells/mm3] 500–9500 2400 1140 1500–7500 3810 3420
Abs Lymph [cells/mm3] 3400–9000 7131 6387 1900–3700 2513 2300
Abs CD3 [cells/mm3] 1900–5900 5027 4747 1200–2600 2042 1754
CD4:CD8 [cells/mm3] 1.34–3.04 2.20 1.23 1.18–2.65 0.97 1.2
Abs CD4 [cells/mm3] 1400–4300 3170 2417 650–1500 844 877
Abs CD8 [cells/mm3] 500–1700 1397 1956 370–1100 867 738
Abs CD56 [cells/mm3] 160–950 267 243 110–480 205 197
Abs CD19 [cells/mm3] 610–2600 1745 1369 270–860 261 441

Ig, immunoglobulin; Hib, Haemophilus influenzae type b; WBC, white blood cell; Hgb, hemoglobin; MCV, mean cell volume; PLT, platelets; ANC, absolute neutrophil count; Abs, absolute; Lymph, lymphocytes. Age-appropriate ranges were identified for immunoglobulins (9), CBC (10), lymphocyte subsets (11) and CD4:CD8 ratio (12).