Table 1.
Effect of Different Tween® 80 Concentrations on Particle Size, Polydispersity Index and Zeta Potential of Blank NLC (Mean ±SD, n=3)
Composition (%w/v) | NLC-0.25 | NLC-0.5 | NLC-1 | NLC-1.25 |
---|---|---|---|---|
Stearic acid | 3 | 3 | 3 | 3 |
Oleic acid | 1 | 1 | 1 | 1 |
Tween® 80 | 0.5 | 1 | 1.5 | 2 |
Water | Up to 50 mL | Up to 50 mL | Up to 50 mL | Up to 50 mL |
PS (nm) | 342.5 ± 7.1 | 224 0.6 ± 8.2 | 102.3 ± 4.6 | 106 ± 3.5 |
PDI | 0.521 ± 0.72 | 0.41 ± 0.43 | 0.267 ± 0.12 | 0.289 ± 0.11 |
ZP (mV) | −28.5 ± 1.5 | −29.6 ± 0.7 | −31.4 ± 1.3 | −27.1 ± 1.7 |