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. 2021 Mar 25;16:2405–2417. doi: 10.2147/IJN.S286896

Table 1.

Effect of Different Tween® 80 Concentrations on Particle Size, Polydispersity Index and Zeta Potential of Blank NLC (Mean ±SD, n=3)

Composition (%w/v) NLC-0.25 NLC-0.5 NLC-1 NLC-1.25
Stearic acid 3 3 3 3
Oleic acid 1 1 1 1
Tween® 80 0.5 1 1.5 2
Water Up to 50 mL Up to 50 mL Up to 50 mL Up to 50 mL
PS (nm) 342.5 ± 7.1 224 0.6 ± 8.2 102.3 ± 4.6 106 ± 3.5
PDI 0.521 ± 0.72 0.41 ± 0.43 0.267 ± 0.12 0.289 ± 0.11
ZP (mV) −28.5 ± 1.5 −29.6 ± 0.7 −31.4 ± 1.3 −27.1 ± 1.7