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. 2021 Mar 18;11:655258. doi: 10.3389/fcimb.2021.655258

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Copyright © 2021 Qiao, Qiu, Tian, Yu, Zhao, Zhang, Zhai and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gastrointestinal transit rate of BALB/c mice after constipation induced by loperamide hydrochloride and administration of different treatments (n = 10). (A) Normal control: no treatment; (B) negative control group: physiological saline; (C) positive control group: phenolphthalein (70 mg/kg body weight); (D) treatment group: P. acidilactici CCFM28 strain; (E) treatment group: P. acidilactici CCFM18 strain; (F) treatment group: P. acidilactici NT17-3 strain; (G) treatment group: P. acidilactici 102H8 strain. The letters a, b, c and d indicate significant differences (P < 0.05) as determined using Duncan’s multiple range test.