Table 5.

Association of MYOM1 gene alterations with demographic and clinicopathological variables in 444 subjects (224 cases and 220 controls)

Parameters	MYOM1 Gly333Gly (G>A; rs2230162)		OR (95% CI)	P value	MYOM1 Gly341Ala (G>C; rs8099021)		OR (95% CI)	P value
	GG	GA+AA			GG	GC+CC
Age
≤30 years	189	78	Ref. (1.00)		00	267	Ref. (1.00)	0.3
>30 years	107	71	0.6 (0.4-0.9)	0.01	00	177	1.5 (0.09-24.2)
Gender
Male	163	107	Ref. (1.00)		00	270	Ref. (1.00)	0.4
Female	133	41	2.1 (1.3-3.2)	0.0002	00	174	1.5 (0.09-24.9)
Smoking Status
Non-Smoker	70	15	Ref. (1.00)		00	85	Ref. (1.00)	0.2
Passive Smoker	195	80	0.52 (0.28-0.96)	0.01	00	275	0.3 (0.01-5.03)	0.4
Active Smoker	31	53	0.12 (0.06-0.25)	<0.0001	00	84	1.01 (0.06-16.4)
Occupation
Student	83	47	Ref. (1.00)		00	130	Ref. (1.00)
Near Workers	105	75	0.80 (0.49-1.26)	0.1	00	180	0.7 (0.04-11.6)	0.4
Others	108	26	2.3 (1.34-4.12)	0.001	00	134	0.97 (0.06-15.6)	0.5
Family History
No	48	32	Ref. (1.00)		00	80	Ref. (1.00)	0.3
Yes	120	24	3.3 (1.7-6.2)	<0.0001	00	144	0.5 (0.03-8.9)
Degree of Myopia
<-6 D	100	24	Ref. (1.00)		00	124	Ref. (1.00)	0.4
≥-6 D	68	32	0.51 (0.27-0.94)	0.01	00	100	1.2 (0.07-20.03)

D; Diopters.