Figure 1.

Interactions between residues of (A) native and (B) mutant nsp7 (yellow), nsp8 (orange) and RdRp (green) proteins. The S25L mutation in nsp7 leads to a H‐bond formation between nsp7 S26 and nsp8 D163, which is not observed in the native RdRp–nsp7–nsp8 supercomplex