Table 4:

Diagnostic performance for stroke detection with incremental study review using receiver operating characteristic–determined thresholds for level of confidence

	Sensitivity		Specificity
	Se% (95% CI)	P Valuea	Sp% (95% CI)	P Valuea
Level of confidence ≥5 vs <5
1) NCCT	40.7 (30.8–50.6)	1 vs 2: .174	70.5 (64.4–76.7)	1 vs 2: .088
2) NCCT + CTA-SI	51.7 (40.9–62.5)	1 vs 3: .048b	78.2 (72.2–84.2)	1 vs 3: .002b
3) NCCT + CTA-SI + CTP	55.9 (45.6–66.3)	2 vs 3: .536	83.3 (78.3–88.3)	2 vs 3: .155
Level of confidence ≤2 vs <2
1) NCCT	9.3 (4.3–14.3)	1 vs 2: .009b	91.9 (88.5–95.2)	1 vs 2: .130
2) NCCT + CTA-SI	26.3 (17.3–35.3)	1 vs 3: <.001b	95.3 (92.5–98.1)	1 vs 3: .691
3) NCCT + CTA-SI + CTP	42.4 (30.6–54.2)	2 vs 3: .030b	91.9 (88.4–95.4)	2 vs 3: .264

Note:—Se indicates sensitivity; Sp, specificity.

^aP value was obtained by a linear regression model of natural log(Se) or log(Sp) for each modality.

^bStatistically significant.