Table 4:

Treatment effects: comparison of changes in relative cerebral activity between the first and second PET assay in patients with hyperthyroidism (effect of treatment with methimazole) and differences between patients with hyperthyroidism after treatment and control subjects

Patients with Hyperthyroidism	Voxel Levels
	Corrected P Value	Z Score	Peak Voxela
			X	Y	Z
Increase
Parahippocampal gyrus (BA 35)b
Left	.006	4.41	−22	−5	−25
Parahippocampal gyrus (BA 28)b
Left	.022	4.17	−18	−11	−21
Superior frontal gyrus (BA 6)b
Right	.009	4.33	14	7	60
Fusiform gyrus (BA 37)b
Left	.005	4.46	−40	−63	−14
Cured compared with healthy controls
Parahippocampal gyrus (BA 35)b
Left	.015	4.29	−22	−5	−25
Parahippocampal gyrus (BA 28)
Left	.068	3.97	−18	−11	−21
Superior frontal gyrus (BA 6)
Right	.395	3.79	14	7	60
Fusiform gyrus (BA 37)b
Left	.040	4.09	−40	−63	−14

^aTalairach coordinates.

^bSurvived at FDR-corrected P < .05.