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. 2021 Jan 18;61(3):180–202. doi: 10.1002/jobm.202000537

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© 2021 Wiley‐VCH GmbH

This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.

PMC Copyright notice

Phylogenetic relationship of various coronavirus spike (S) glycoproteins. The sequences downloaded from UniprotKB and GenBank website were clustered according to generas, namely, Alphacoronavirus, Betacoronavirus, Gammacoronavirus, and Deltacoronavirus. Multiple sequence alignment (MSA) was build using the MUSCLE tool of MEGAX software and phylogeny was inferred using maximum likelihood method with model of substitution: WAG + F + I+ G4 and 1000 bootstraps employing IQ‐Tree webserver (http://iqtree.cibiv.univie.ac.at/)