TABLE 1.
Donor demographics and characteristics
| Total donations a N = 309 (%) | Donations without adverse reactions N = 293 (%) | Adverse reactions N = 16 (%) | |
|---|---|---|---|
| Plasma donation history | |||
| First time | 181 (58.6%) | 171 (58.4%) | 10 (62.5%) |
| Repeat | 128 (41.4%) | 122 (41.6%) | 6 (37.5%) |
| Sex | |||
| Male | 186 (60.2%) | 176 (60.1%) | 10 (62.5%) |
| Female | 123 (39.8%) | 117 (39.9%) | 6 (37.5%) |
| Age group, years | |||
| Mean ± SD | 38 ± 8 | 38 ± 8 | 40 ± 9 |
| Range | 20–55 | 20–55 | 21‐52 |
| ≤24 | 15 (4.9%) | 13 (4.4%) | 2 (12.5%) |
| 25‐29 | 26 (8.4%) | 25 (8.5%) | 1 (6.3%) |
| 30‐34 | 66 (21.4%) | 63 (21.5%) | 3 (18.8%) |
| 35‐39 | 84 (27.2%) | 82 (28.0%) | 2 (12.5%) |
| 40‐44 | 42 (13.6%) | 40 (13.7%) | 2 (12.5%) |
| 45‐49 | 49 (15.8%) | 46 (15.7%) | 3 (18.7%) |
| ≥50 | 27 (8.7%) | 24 (8.2%) | 3 (18.7%) |
| Weight (Kg) | |||
| Mean ± SD | 69 ± 13 | 69 ± 13 | 72 ± 15 |
| Range | 45–117 | 45–117 | 49‐113 |
| 45‐59 | 80 (25.9%) | 77 (26.3%) | 3 (18.8%) |
| 60‐74 | 129 (41.7%) | 123 (42.0%) | 6 (37.5%) |
| 75‐89 | 80 (25.9%) | 75 (25.6%) | 5 (31.2%) |
| ≥90 | 20 (6.5%) | 18 (6.1%) | 2 (12.5%) |
| Pre‐donation systolic BP (mmHg) | |||
| Mean ± SD | 122 ± 12 | 123 ± 12 | 120 ± 13 |
| Range | 84‐140 | 90‐140 | 84–140 |
| <100 | 18 (5.5%) | 15 (5.1%) | 3 (18.7%) |
| 100‐130 | 200 (64.7%) | 189 (64.5%) | 11 (68.8%) |
| 130‐140 | 91 (29.8%) | 89 (30.4%) | 2 (12.5%) |
| Pre‐donation diastolic BP (mm Hg) | |||
| Mean ± SD | 80 ± 8 | 80 ± 8 | 80 ± 6 |
| Range | 60‐90 | 60‐90 | 68‐90 |
| <70 | 42 (13.6%) | 39 (13.3%) | 3 (18.7%) |
| 70‐85 | 161 (52.1%) | 152 (51.9%) | 9 (56.3%) |
| 85‐90 | 106 (34.3%) | 102 (34.8%) | 4 (25%) |
| Pre‐donation pulse (bpm) | |||
| Mean ± SD | 87 ± 10 | 87 ± 10 | 89 ± 10 |
| Range | 62‐107 | 62‐107 | 66‐100 |
| <65 | 3 (1.0%) | 3 (1.0%) | 0 (0%) |
| 65‐90 | 190 (61.5%) | 183 (62.5%) | 7 (43.8%) |
| >90 | 116 (37.5%) | 107 (36.5%) | 9 (56.2%) |
| Hemoglobin, Hb (g/L) | |||
| Mean ± SD | 142 ± 12 | 142 ± 13 | 141 ± 11 |
| Range | 115‐175 | 115–175 | 125‐161 |
| <120 | 3 (1.0%) | 3 (1.0%) | 0 (0%) |
| 120‐134 | 102 (33.0%) | 95 (32.4%) | 7 (43.8%) |
| 135‐150 | 118 (38.2%) | 113 (38.6%) | 5 (31.2%) |
| >150 | 86 (27.8%) | 82 (28.0%) | 4 (25%) |
| Days of disease onset to donation | |||
| Mean ± SD | 52 ± 12b | 51 ± 12b | 42 ± 10 |
| Range | 17‐85 | 17‐93 | 23‐56 |
| <28 | 10 (3.2%) | 7 (2.4%) | 3 (18.8%) |
| 28‐42 | 66 (21.4%) | 61 (20.8%) | 5 (31.2%) |
| 43‐56 | 138 (44.7%) | 130 (44.4%) | 8 (50%) |
| 57‐70 | 84 (27.2%) | 84 (28.7%) | 0 (0%) |
| ≥71 | 9 (2.9%) | 9 (3.1%) | 0 (0%) |
| Volume of per‐donation (mL) | |||
| 200 | 61(19.7%) | 61 (20.8%) | 0 (0%) |
| 300 | 42 (13.6%) | 40 (13.7%) | 2 (12.5%) |
| 400 | 202 (65.4%) | 191 (65.2%) | 11 (68.8%) |
| 600 | 4 (1.3%) | 1 (0.3%) | 3 (18.7%) |
| ABO Blood type | |||
| Type A | 121 (39.2%) | 117 (40.0%) | 4 (25.0%) |
| Type AB | 28 (9.0%) | 27 (9.2%) | 1 (6.3%) |
| Type B | 84 (27.2%) | 76 (25.9%) | 8 (50.0%) |
| Type O | 76 (24.6%) | 73 (24.9%) | 3 (18.7%) |
| Symptoms of adverse reactions | |||
| Discomfort, weakness, dizziness, sweating, or nausea | ‐ | ‐ | 14 (87.5%) |
| More than one symptom | ‐ | ‐ | 2 (12.5%) |
a
All donors made only one plasma donation events.
b
Two data missing.