Table 5.
Sensitivity, specificity, positive predictive value, negative predictive value, and results of the receiver operating characteristic curve for MPV, CRP, PCT, WBC, D‐dimer and NT‐pro‐BNP in hospitalized confirmed COVID‐19 patients
| Cut‐off value | Sensitivity (%) | Specificity (%) | PPV | NPV | Youden's index | AUC (95% CI) | SE | p |
|---|---|---|---|---|---|---|---|---|
| MPV >9.8 fL | 60.00 | 58.67 | 28.9 | 83.9 | 0.1867 | 0.612 (0.549–0.673) | 0.0430 | .0093 |
| CRP >30.79 mg/L | 29.09 | 95.88 | 30.3 | 84.3 | 0.2497 | 0.630 (0,566–0.690) | 0.0459 | .0047 |
| PCT >0.13 µg/L | 70.00 | 84.62 | 58.3 | 90.2 | 0.5462 | 0.760 (0.655–0.846) | 0.0780 | .0009 |
| WBC >8520/mm3 | 47.27 | 76.02 | 27.6 | 83.7 | 0.2329 | 0.628 (0,565–0.688) | 0.0448 | .0042 |
| D‐dimer >621 µg/L | 67.50 | 79.63 | 71.1 | 76.1 | 0.4713 | 0.776 (0.678–0.856) | 0.0515 | <.0001 |
| NT‐pro‐BNP >57 ng/L | 72.4 | 80.4 | 72.4 | 80.5 | 0.5290 | 0.774 (0.658–0.865) | 0.0629 | <.0001 |
Abbreviations: ALC, absolute lymphocyte count; ANC, absolute neutrophil count; COVID‐19, coronavirus disease 2019; CRP, C‐reactive protein; Hb, Hemoglobin; MPV, mean platelet volume; NLR, neutrophil‐to‐lymphocyte ratio; NT‐pro‐BNP, N‐terminal‐pro‐brain natriuretic peptide; PCT, procalcitonin; PLT, platelet count; WBC, white blood cell.