TABLE 1.
Laboratory results upon admission, deterioration, and discharge. Chest X‐rays
| Investigations | 16/11/2020 (At admission) | 21/11/2020 (after Pain crisis‐Acute chest syndrome) | Latest Laboratories (after exchange transfusion) |
| ECG | Sinus rhythm with QTC 436 ms | ||
| ABO | AB+ | ||
| WBC | 4.7 × 103/uL | 5.6 × 103/UL | 4.3 × 103/uL |
| RBC | 4.6 × 106/uL | 2.7 × 106/uL | 3.5 × 106/uL |
| Hgb | 9.7 gm/dL | 5.8 gm/dL | 8.7 gm/dL |
| Hct | 30.1% | 17.8% | 26.5% |
| MCV | 64.7 fL | 66.4 fL | 76.1 fL |
| MCH | 20.9 pg | 21.6 pg | 25.0 pg |
| MCHC | 32.2 gm/dL | 32.6 gm/dL | 32.8 gm/dL |
| ANC | 2.2 × 103/uL | 4.1 × 103/uL | 3.0 × 103/uL |
| Lymphocyte Auto # | 2.2 × 103/uL | 1.1 × 103/uL | 1.1 × 103/uL |
| Retic # (percentage) | 105.3 × 103/uL (4.0%) | 81.7 × 103/uL (2.3%) | |
| Platelet | 139 × 103/uL | 93 × 103/uL | 112 × 103/uL |
| Prothrombin Time | 12.5 s | 10.9 s | |
| INR | 1.2 | 1.0 | |
| D‐Dimer | 0.89 mg/L | 5.36 mg/L | 4.01 mg/L |
| Fibrinogen | 6.09 gm/L | 4.18 gm/L | |
| Urea | 3.0 mmol/L | 3.1 mmol/L | 3.7 mmol/L |
| Creatinine | 53 umol/L | 56 umol/L | 43 umol/L |
| eGFR | >60 mL/min | ||
| Alk Phos | 113 U/L | 282 U/L | 201 U/L |
| ALT | 16 U/L | 22 U/L | 19 U/L |
| AST | 19 U/L | 38 U/L | 18 U/L |
| G6PD Screen | Deficient | ||
| CRP | 11.1 mg/L | 270.8 mg/L | 25.9 mg/L |
| Ferritin | 1,502.0 ug/L | 5,546.0 ug/L | 3,785.0 ug/L |
| LDH | 805 U/L | ||
| Haptoglobin | <10 mg/dL | ||
| Hemoglobin electrophoresis |
Hgb A: 0.0% Hgb A2: 4.2% Hgb F: 17.0% Hgb S: 78.8% |
Hgb A: 66.8% Hgb A2: 5.4% Hgb F: 5.4% Hgb S: 22.4% |