TABLE 4.
Univariate analysis for main outcome (compound of death and major bleeding)
| Variable | Death or major bleeding | No death or major bleeding | P‐value | OR | 95% CI |
|---|---|---|---|---|---|
| Male | 20 (32.2%) | 42 (67.7%) | 0.363 | 0.652 | 0.259‐1.640 |
| >65 y | 14 (27.5%) | 37 (72.5%) | 0.729 | 0.858 | 0.360‐2.045 |
| BMI > 30 | 8 (25.0%) | 24 (75.0%) | 0.734 | 0.843 | 0.316‐2.253 |
| Hospital admission | 23 (34.8%) | 43 (65.2%) | 0.079 | 2.496 | 0.898‐6.935 |
| ICU admission | 15 (65.2%) | 8 (34.8%) | <0.001 | 8.437 | 2.981‐23.882 |
| Recent bleeding | 0 (0.0%) | 3 (100%) | – | – | |
| Anemia | 19 (40.4%) | 28 (59.6%) | 0.021 | 2.918 | 1.179‐7.221 |
| Platelets <150 000/mm3 | 10 (50.0%) | 10 (50.0%) | 0.025 | 3.211 | 1.156‐8‐919 |
| Lymphocytes <1200/mm3 | 22 (33.3%) | 44 (66.7%) | 0.141 | 2.167 | 0.774‐6.068 |
| Altered prothrombin time | 20 (27.0%) | 54 (73.0%) | 0.402 | 1.543 | 0.560‐4.254 |
| Creatinine > 1.2 mg/dL | 7 (50.0%) | 7 (50.0%) | 0.071 | 2.909 | 0.912‐9.280 |
| Creatinine > 1.5 mg/dL | 2 (40.0%) | 4 (60%) | 0.584 | 1.679 | 0.263‐10.712 |
| D‐dimer > 1000 ng/mL | 21 (25.0%) | 63 (75.0%) | 0.041 | 0.286 | 0.086‐0.951 |
| D‐dimer > 5000 ng/mL | 11 (32.4%) | 23 (67.6%) | 0.580 | 1.294 | 0.519‐3.226 |
| D‐dimer > 10 000 ng/mL | 5 (25.0%) | 15 (75.0%) | 0.671 | 0.783 | 0.253‐2.421 |
| Cancer | 5 (71.4%) | 2 (28.6%) | 0.024 | 7.187 | 1.296‐39.856 |
| Type of VTE: PE | 18 (28.6%) | 45 (71.4%) | 0.902 | 0.945 | 0.386‐2.315 |
Abbreviations: CI, confidence interval; BMI, body‐mass index; ICU, intensive care unit; VTE, venous thromboembolism; PE, pulmonary embolism.