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. 2021 Mar 18;11:574260. doi: 10.3389/fonc.2021.574260

Figure 1.

Figure 1

The expression of PLAU1 in HNSCC tissues. (A) The PLAU1 expression level was significantly upregulated in HNSCC tissues, compared to that in paired adjacent normal tissues (****p < 0.0001). (B) Upregulated PLAU1 levels were correlated with increased tumor size, lymph node metastasis, and advanced tumor stage. (C) ROC curves of PLAU1 for discriminating HNSCC tissues from adjacent normal tissues. (D) Kaplan-Meier analysis of overall survival. Compared with patients with low PLAU1 expression, those with high PLAU1 expression had a significantly lower overall survival rate. ROC: receiver operating characteristic curve.