Figure 1.
Effect of (S S)-DS-ONJ in the cellular viability in Bv.2 microglial cells. (A) Chemical structures of the sp2-IGLs (S S)-DS-ONJ, (S R)-DS-ONJ and DSO2-ONJ. (B) Bv.2 microglial cells were treated for 24 h with (S S)-DS-ONJ (1–10 μM) and viability was determined by crystal violet staining. Colorimetric quantification results presented as mean ± SEM (n = 5 independent experiments). The fold changes are presented relative to basal values. *p ≤ 0.05 vs the basal values (two-way ANOVA followed by Bonferroni t-test.)