Table 1.

The clinical characteristics of multiple episodes in the patient with SPTCL analyzed in this study.

The onset of symptoms (months)	Subcutaneous lesions		Other lesions	Systemic symptoms	HLH	EBV infection	Histopathological characteristics			Immunophenotype		TCR gene rearrangement
	Location	Diameter					Infiltration range	Infiltration cell	Types	IHC	Level of Ki‐67
6	Single lesion: left clavicle	1cm	Enlarged lymph nodes of the groin	None	No	No	NA	NA	NA	NA	NA	NA
12	Single lesion: left clavicle	6cm	Enlarged lymph nodes in the head of the pancreas	None	No	No	Dermis and subcutaneous tissue	Lymphocytes and histocytes	Inflammation	CD1α (-), CD34 (+), CD45 (+), CD68 (+)	5%	NA
18	Multiple lesions: right thigh and left hip	3-5cm	Enlarged lymph nodes of the neck, underarms, mediastinum, and groin	Fever	No	No	Epidermis, dermis and subcutaneous fatty tissue	Heterotypic lymphocytes, histocytes and karyokinesis	Panniculitis-like	CD20 (-), CD3 (+), CD5 (+), CD7 (+), CD4 (-), CD8 (+), TIA (+), GB (+/-), CD56 (-), EBER (-)	40-50%	NA
22	Single lesion: right shoulder	2cm	Enlarged lymph nodes of the neck, underarms, mediastinum, and groin	None	No	No	Dermis and subcutaneous fatty tissue	Heterotypic lymphocytes, histocytes, karyokinesis and karyorrhexis	Panniculitis-like	CD20 (-), CD3 (+), CD5 (+), CD7 (+), CD4 (+/-), CD8 (+), TIA (+/-), GB (+/-), Perforin (+/-), CD56 (-), EBER (-)	20%	Clonal TCR-Beta gene rearrangements

EBV, Epstein-Barr virus; HLH, hemophagocytic lymphohistiocytosis; SPTCL, subcutaneous panniculitis-like T-cell lymphoma.