Table 1. Crude Values for Outcomes and Covariates at Baseline and Follow-Up Visits.
| SWAN,a,b mean (SD) | ||||
|---|---|---|---|---|
| Visit 7 (n = 1528-1724) | Visits 8 and 9 (n = 1460-1604) | Visit 12 (n = 1438-1489) | Visit 15 (n = 1226-1270) | |
| Outcome | ||||
| Symbol digit modalities test | 58.19 (10.72) | 58.94 (10.96) | 57.58 (10.78) | 55.70 (10.81) |
| Missing data, No. (%) | 6 (0.35) | 7 (0.44) | 3 (0.20) | 7 (0.55) |
| Digit span backwards | 6.95 (2.32) | 6.96 (2.32) | 6.99 (2.30) | 6.80 (2.25) |
| Missing data, No. (%) | 43 (2.50) | 33 (2.06) | 18 (1.21) | 35 (2.76) |
| East Boston Memory Test-Delayed | 10.27 (1.73) | 10.43 (1.65) | 10.34 (1.68) | 10.15 (1.68) |
| Missing data, No. (%) | 2 (0.12) | 1 (0.06) | 1 (0.07) | 1 (0.08) |
| Primary exposure | ||||
| Sport and exercise physical activity level | 2.79 (0.96) | 2.79 (0.99) | 2.89 (1.03) | 2.90 (1.03) |
| Missing data, No. (%) | 195 (11.35) | 144 (8.98) | 16 (1.07) | 30 (2.36) |
| Total physical activity level | 7.59 (1.64) | 7.55 (1.71) | 7.66 (1.82) | 7.57 (1.82) |
| Missing data, No. (%) | 199 (11.58) | 147 (9.16) | 18 (1.21) | 34 (2.68) |
| Covariate, No. (%) | ||||
| Financial hardship | ||||
| High level | 73 (4.31) | 59 (3.77) | 71 (4.85) | 22 (1.77) |
| Moderate level | 347 (20.48) | 307 (19.60) | 309 (21.09) | 186 (14.94) |
| Missing data, No. (%) | 24 (1.40) | 38 (2.37) | 24 (1.61) | 25 (1.97) |
| Hormone therapy use | 278 (16.53) | 180 (11.42) | 68 (4.73) | 33 (2.69) |
| Missing data, No. (%) | 36 (2.10) | 28 (1.75) | 51 (3.43) | 44 (3.46) |
| Depressive symptoms | 345 (20.31) | 324 (20.66) | 264 (17.73) | 201 (15.83) |
| Missing data, No. (%) | 19 (1.11) | 36 (2.24) | 0 | 0 |
| Sleep problems | 482 (28.37) | 446 (28.30) | 474 (31.96) | 455 (36.11) |
| Missing data, No. (%) | 19 (1.11) | 28 (1.75) | 6 (0.40) | 10 (0.79) |
| Vasomotor symptoms | 454 (26.49) | 428 (26.88) | 256 (17.24) | 140 (11.10) |
| Missing data, No. (%) | 4 (0.23) | 12 (0.75) | 4 (0.27) | 9 (0.71) |
| Anxiety symptoms | 538 (31.39) | 485 (30.46) | 361 (24.36) | 254 (20.17) |
| Missing data, No. (%) | 4 (0.23) | 12 (0.75) | 7 (0.47) | 11 (0.87) |
| Diabetes | 116 (6.75) | 140 (8.73) | 186 (12.49) | 189 (14.88) |
| Hypertension | 676 (39.62) | 648 (40.53) | 765 (51.45) | 730 (57.71) |
| Missing data, No. (%) | 12 (0.70) | 5 (0.31) | 2 (0.13) | 5 (0.39) |
| BMI | 28.52 (7.09) | 28.51 (7.06) | 28.96 (7.22) | 28.65 (6.86) |
| Missing data, No. (%) | 15 (0.87) | 15 (0.94) | 15 (1.01) | 9 (0.71) |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); SWAN, Study of Women’s Health Across the Nation.
a
SWAN follow-up visit 7 is the baseline visit for the current analysis, and SWAN follow-up visit 15 is the final visit. Visits included in this table were selected to be approximately equally spaced across the study’s observation period. Due to budget constraints, approximately half of the SWAN cohort underwent cognitive tests at follow-up visit 8 and the remainder at follow-up visit 9.
b
Range in sample sizes are due to missing values for some variables.