FIGURE 4.

Forest plot reporting the summary of the receiver operating characteristic (ROC) analyses to assess the diagnostic accuracy of neutrophil elastase (NE), myeloperoxidase (MPO)‐conjugated DNA, histone‐DNA, cell‐free dsDNA, and DNase activity for the prediction of disease‐related outcomes. For each biomarker, a ROC analysis was performed using the following classification variables: intensive care unit admission, heart decompensation, liver injury, kidney injury, respiratory failure, blood oxygen saturation <85%, number of affected organs ≥2, and NEWS 2 score ≥5. For each ROC analysis, the summary results were reported using the area under the ROC curve, the 95% confidence interval, and the associated p‐value (Table S3)