Table 3.
Age, BMI and laboratory values
| Laboratory value, median (IQR) | Outcome | P‐value | |
|---|---|---|---|
| Yes | No | ||
| Oxygen supplementation | |||
| n | 39 | 64 | |
| Age (years) | 68 (55–72) | 57.5 (50.3–63.8) | <0.01 |
| BMI (kg/m²) | 29.1 (24.8–33.7) | 26.7 (22.9–31.2) | 0.24 |
| Peak LDH (U/L) | 455 (373–539) | 266 (235–318) | <0.01 |
| Peak AST (U/L) | 85 (55–127) | 37 (28–58) | <0.01 |
| Peak ALT (U/L) | 85 (53–129) | 41 (26.3–68) | <0.01 |
| Peak CRP (mg/L) | 120 (62.7–180) | 6.3 (1.9–24.7) | <0.01 |
| Nadir platelet count (×109/L) | 160 (125–195) | 203 (177–239) | <0.01 |
| Nadir lymphocyte count (×109/L) | 0.78 (0.5–1.2) | 1.23 (0.9–1.7) | <0.01 |
| Neutrophil: lymphocyte (at lymphocyte nadir) | 6.3 (4.1–13.4) | 2.2 (1.7–3.2) | <0.01 |
| Nadir eosinophil count (×109/L) | 0 (0.0–0.01) | 0.03 (0.01–0.06) | <0.01 |
| ICU admission | |||
| n | 18 | 85 | |
| Age (years) | 66.5 (57.5–74.3) | 60 (51–67.5) | 0.04 |
| BMI (kg/m²) | 27.6 (24.1–30.9) | 27.2 (23.9–31.6) | 0.78 |
| Peak LDH (U/L) | 479 (416.3–673.8) | 295 (245–381) | <0.01 |
| Peak AST (U/L) | 99 (77.5–166) | 42.5 (31–70.8) | <0.01 |
| Peak ALT (U/L) | 95.5 (62.8–183.3) | 53 (28–83.5) | <0.01 |
| Peak CRP (mg/L) | 143.3 (83.8–199.2) | 11.8 (3.3–60.3) | <0.01 |
| Nadir platelet count (×109/L) | 167.5 (107–195) | 194 (159–236) | 0.05 |
| Nadir lymphocyte count (×109/L) | 0.61(0.43–1.1) | 1.2 (0.9–1.6) | <0.01 |
| Neutrophil: lymphocyte (at lymphocyte nadir) | 9.4 (5.4–21.2) | 2.6 (1.8–4.0) | <0.01 |
| Nadir eosinophil count (×109/L) | 0 (0–0.003) | 0.02 (0.01–0.05) | <0.01 |
| Death | |||
| n | 4 | 99 | |
| Age (years) | 74.5 (65–75.8) | 60 (51–68) | 0.02 |
| BMI (kg/m²) | 25.7 (NA)† | 27.4 (24.2–31.4) | 0.57 |
| Peak LDH (U/L) | 682 (497–1130) | 316.5 (254.5–426) | <0.01 |
| Peak AST (U/L) | 301.5 (120.8–595.5) | 51.5 (33–80.5) | <0.01 |
| Peak ALT (U/L) | 132 (72.5–403.8) | 55 (30–93) | 0.03 |
| Peak CRP (mg/L) | 121 (96.9–154.6) | 23 (3.8–84) | 0.03 |
| Nadir platelet count (×109/L) | 130 (96–186) | 192 (150–228) | 0.05 |
| Nadir lymphocyte count (×109/L) | 0.5 (0.3–1.8) | 1.1 (0.78–1.6) | 0.15 |
| Neutrophil: lymphocyte (at lymphocyte nadir) | 22 (10.6–30.4) | 2.96 (10.6–30.4) | <0.01 |
| Nadir eosinophil count (×109/L) | 0 (0–0) | 0.01 (0–0.04) | <0.01 |
P‐values calculated with Mann−Whitney U‐test.
†
Insufficient data to calculate IQR.
ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; CRP, C‐reactive protein; IQR, interquartile range; LDH, lactate dehydrogenase.