Table 3. Adjusted Risk of Shorter Time to Heal by Propranolol Dose.

Variable	HR (95% CI)a	P value
Model 1
Propranolol dose, mg/kg/d
>1	1 [Reference]	[Reference]
≤1	2.035 (1.11-3.73)	.02
IH size ≤5 cm2	1 [Reference]	[Reference]
>5 to ≤10	0.680 (0.38-1.22)	.19
>10 to ≤50	0.371 (0.20-0.69)	.002
>50 to ≤100	0.307 (0.12-0.79)	.02
>100	0.670 (0.26-1.74)	.41
Model 2
Propranolol dose, mg/kg/d
≥2	1 [Reference]	[Reference]
1-2	1.177 (0.69-2.00)	.55
≤1	2.145 (1.14-1.03)	.02
IH size ≤5 cm2	1 [Reference]	[Reference]
>5 to ≤10	0.658 (0.36-1.19)	.17
>10 to ≤50	0.356 (0.19-0.67)	.001
>50 to ≤100	0.312 (0.12-0.81)	.02
>100	0.668 (0.26-1.74)	.41
Model 3
Propranolol dose, mg/kg/d
≥2	1 [Reference]	[Reference]
<2	1.44 (0.91- 2.27)	.12
IH size ≤5 cm2	1 [Reference]	[Reference]
>5 to ≤10	0.640 (0.35-1.16)	.14
>10 to ≤50	0.368 (0.20-0.69)	.002
>50 to ≤100	0.345 (0.13-0.89)	.03
>100	0.829 (0.33-2.07)	.69

Abbreviations: HR, hazard ratio; IH, infantile hemangioma.

^aAn HR greater than 1 is associated with shorter heal times; HR less than 1 is associated with longer heal times.