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. 2021 Mar 31;78(7):1–9. doi: 10.1001/jamapsychiatry.2021.0228

Table 1. Overview About the PGS Candidate Features in the Data Seta.

Source PGSa Phenotype
Wray et al,41 2018 EA_PGS3_MDD2_PGC18 Major depressive disorder
Schizophrenia Working Group of the Psychiatric Genomics Consortium,18 2014 PGS_SCZ_PGC14 Schizophrenia
Duncan et al,42 2018 EA_PGS3_PTSDEA_PGC18 Posttraumatic stress disorder
Demontis et al,43 2019 EA_PGS3_ADHD_PGC17 Attention-deficit/hyperactivity disorder
Arnold et al,44 2018 EA_PGS3_OCD_IOCDF17 Obsessive-compulsive disorder
Psychiatric GWAS Consortium Bipolar Disorder Working Group,20 2011 EA_PGS3_BIP_PGC11 Bipolar disorder
de Moor et al,45 2015 PGS_neuroticism_SSGAC16 Neuroticism
Ripke et al,46 2013 PGS_depsymp_SSGAC16 Depressive symptoms
Otowa et al,47 2016 EA_PGS3_ANXFS_ANGST16 Anxiety symptoms continuous
Okbay et al,48 2016 PGS_well-being_SSGAC16 Well-being
EA_PGS3_EXTRAV_GPC17 Extraversion
Davies et al,49 2015 PGS_GenCog_CHARGE15 Cognitive function
Lee et al,50 2018 PGS_EDU3_SSGAC18 Educational attainment
Bolton et al,51 2014 EA_PGS3_CRTSL_CORNET14 Cortisol
Furberg et al,52 2010 PGS_EvrSmk_TAG10 Smoking behavior
Shungin et al,53 2015 PGS_WC_GIANT15 Waist circumference
PGS_WHR_GIANT15 Body fat distribution
Locke et al,54 2015 PGS_BMI_GIANT15 Body mass index
Willer et al,55 2013 EA_PGS3_HDL_GLGC13 High-density lipoprotein cholesterol
EA_PGS3_LDL_GLGC13 Low-density lipoprotein cholesterol
EA_PGS3_TC_GLGC13 Total cholesterol

Abbreviations: GWAS, genome-wide association study; HRS, Health and Retirement Study; PGS, polygenic score.

a

These PGSs were selected for their potential relevance for discriminating heterogeneous stress responses based on previous analyses of the HRS data set.40