Table 1. Overview About the PGS Candidate Features in the Data Seta.
| Source | PGSa | Phenotype |
|---|---|---|
| Wray et al,41 2018 | EA_PGS3_MDD2_PGC18 | Major depressive disorder |
| Schizophrenia Working Group of the Psychiatric Genomics Consortium,18 2014 | PGS_SCZ_PGC14 | Schizophrenia |
| Duncan et al,42 2018 | EA_PGS3_PTSDEA_PGC18 | Posttraumatic stress disorder |
| Demontis et al,43 2019 | EA_PGS3_ADHD_PGC17 | Attention-deficit/hyperactivity disorder |
| Arnold et al,44 2018 | EA_PGS3_OCD_IOCDF17 | Obsessive-compulsive disorder |
| Psychiatric GWAS Consortium Bipolar Disorder Working Group,20 2011 | EA_PGS3_BIP_PGC11 | Bipolar disorder |
| de Moor et al,45 2015 | PGS_neuroticism_SSGAC16 | Neuroticism |
| Ripke et al,46 2013 | PGS_depsymp_SSGAC16 | Depressive symptoms |
| Otowa et al,47 2016 | EA_PGS3_ANXFS_ANGST16 | Anxiety symptoms continuous |
| Okbay et al,48 2016 | PGS_well-being_SSGAC16 | Well-being |
| EA_PGS3_EXTRAV_GPC17 | Extraversion | |
| Davies et al,49 2015 | PGS_GenCog_CHARGE15 | Cognitive function |
| Lee et al,50 2018 | PGS_EDU3_SSGAC18 | Educational attainment |
| Bolton et al,51 2014 | EA_PGS3_CRTSL_CORNET14 | Cortisol |
| Furberg et al,52 2010 | PGS_EvrSmk_TAG10 | Smoking behavior |
| Shungin et al,53 2015 | PGS_WC_GIANT15 | Waist circumference |
| PGS_WHR_GIANT15 | Body fat distribution | |
| Locke et al,54 2015 | PGS_BMI_GIANT15 | Body mass index |
| Willer et al,55 2013 | EA_PGS3_HDL_GLGC13 | High-density lipoprotein cholesterol |
| EA_PGS3_LDL_GLGC13 | Low-density lipoprotein cholesterol | |
| EA_PGS3_TC_GLGC13 | Total cholesterol |
Abbreviations: GWAS, genome-wide association study; HRS, Health and Retirement Study; PGS, polygenic score.
These PGSs were selected for their potential relevance for discriminating heterogeneous stress responses based on previous analyses of the HRS data set.40