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. 2021 Jan 18;41(4):1965–1998. doi: 10.1002/med.21783

Figure 16.

Figure 16

Benzotriazole‐based inhibitors: (A) chemical structures and (B) the proposed mechanism for the benzotriazole ester of inhibitors reacted with the protease. (C–E) The binding modes of the representative benzotriazole‐based inhibitors with various 3CLpros [Color figure can be viewed at wileyonlinelibrary.com]