TABLE 3.
Maternal outcomes
| Review | No. of pregnant women a | No. delivered a | Maternal death, n/N (%) b | Admission to ICU, n/N (%) b | Mechanical ventilation required, n/N (%) b | Delivery <37 weeks, n/N (%) b | Delivery <34 weeks, n/N (%) b | Preterm rupture of membranes, n/N (%) b | Cesarean delivery, n/N (%) b |
|---|---|---|---|---|---|---|---|---|---|
| AbdelMassih (2020) 21 | 1787 | 1787 | N/A | N/A | N/A | 3 | 1 | N/A | N/A |
| Akhtar (2020) 22 | 156 | N/A | 8 | N/A | 11 | 27 | N/A | 12 | 66 |
| Allotey c (2020) 23 | 11 432 | N/A | 73/11 580 (0%; 95% CI 0%–1%) | 323/10 901 (4%; 95% CI 2%–7%) | 155/10 713 (3%; 95% CI 1%–5%) | 386/1872 (17%; 95% CI 13%–21%) | N/A | 28/436 (5%; 95% CI 3%–8%) | 1060/1933 (65%; 95% CI 57%–73%) |
| Arabi c (2020) 24 | 50 | N/A | N/A | N/A | N/A | (20%; 95% CI 4%–4.1%) | N/A | N/A | 47 (100%; 95% CI 95%–100%) |
| Ashraf (2020) 25 | 90 | N/A | 1 | 3 | 3 | 29 | N/A | 16 | 81 |
| Banaei (2020) 26 | 123 | N/A | 0 | 1 | 1 | 30 | N/A | N/A | 99 |
| Capobianco c (2020) 27 | 114 | N/A | 0 | 3 (13%; 95% CI 4%−25%) | N/A | 22 (23%; 95% CI 11%−39%) | N/A | 5 | 95 (88%; 95% CI 82%−94%) |
| Chamseddine (2020) 28 | 164 | 110 | 1/163 (0.6%) | N/A | N/A | 26/128 (20%) | N/A | 4/110 (3.6%) | 93/110 (84.5%) |
| Chang (2020) 29 | 18 | 18 | N/A | N/A | N/A | 10/18 (56%) | N/A | N/A | 16/18 (89%) |
| Chi (2020) 30 | 107 | N/A | N/A | 2/107 | N/A | 25/105 (23.8%) | N/A | N/A | 92/105 (87.6%) |
| Della Gatta (2020) 31 | 51 | 48 | N/A | 2 | 1 | 15 | N/A | 9/34 (26.5%) | 46/48 (95.8%) |
| Dhir (2020) 32 | 2035 | 1184 | N/A | N/A | N/A | 297/1168 (25%) | N/A | N/A | 730/1168 (65%) |
| Di Mascio c (2020) 11 | 41 | 41 | 0/41 (0%) | 2/32 (6.3%) | 1/31 (3.2%) | 14/32 (43.8%) | 4/32 (12.5%) | 5/31 (16.1%) | 38/41 (92.7%) |
| Diriba c (2020) 33 | 1271 | N/A | 8/523 (1.5%; 95% CI 1.2%–9.6%) | 53/186 (28.5%; 95% CI 23.1%–54.4%) | N/A | 86/602 (14.3%; 95% CI 9.2%–33.2%) | 61/682 (8.9%; 95% CI 6.1%–19.3%) | 16/179 (8.9%; 95% CI 5.5%–14.6%) | 426/747 (57%; 95% CI 48.9%–78.7%) |
| Duran (2020) 34 | 195 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | 48 |
| Elshafeey (2020) 35 | 385 | 252 | 1 | 17/385 (4.4%) | 6/385 (1.6%) | 39/256 (15.2%) | N/A | N/A | 175/252 (69.4%) |
| Furlan (2020) 36 | 284 | N/A | N/A | 6/284 (2.1%) | N/A | 60 | 3 | N/A | 149 |
| Gajbhiye (2020) 37 | 441 | 387 | 9/441 (2%) | (11%) | (11%) | /380 (26%) | N/A | /344 (9%) | (80%) |
| Gao (2020) 38 | 236 | N/A | N/A | N/A | N/A | 27/116 (23.3%) | N/A | N/A | 129/187 (69%) |
| Gordon (2020) 39 | N/A | N/A | N/A | N/A | N/A | 3/9 (33%) | 2/9 (22%) | N/A | 6/7 (86%) |
| Huntley (2020) 40 | 538 | 435 | 0/348 (0%) | 8/263 (3%) | N/A | 57/284 (20%) | N/A | N/A | 332/392 (85%) |
| Juan d (2020) 41 | 295 | 219 | 7/295 (2.4%) | 12/253 (4.7%) | 3/170 (1.8%) | N/A | N/A | N/A | 171/219 (78.1%) |
| Jutzeler (2020) 42 | N/A | N/A | 0/9 (0%) | 1/1 | N/A | N/A | N/A | N/A | N/A |
| Kasraeian c (2020) 43 | 87 | N/A | 0/87 (0%; 95% CI 0%–7%) | /32 (2.7%) | N/A | /41 (61.2%) | N/A | 4/31 (13.9%) | /69 (92.2%) |
| Khalil c (2020) 44 | 2567 | 746 | 43/2468 (0.9%; 95% CI 0.4%–2.3%) | 159/1591 (7.0%; 95% CI 4.4%–10.9%) | 92/1680 (3.4%; 95% CI 1.5%–7.7%) | 183/746 (21.8%; 95% CI 14.6%−31.3%) | 13/147 (3.3%; 95% CI 0.2%–31.9%) | N/A | 390/746 (48.3%; 95% CI 34.1%–62.7%) |
| Khan (2020) 45 | 101 | 56 | 1/101 (1%) | N/A | N/A | 17/56 (30%) | N/A | N/A | 47/56 (84%) |
| Kotlyar (2020) 46 | 1566 | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
659/901 (73%) 32/44 (73%) e |
| Lopes de Sousa (2020) 47 | 755 | 587 | 8/755 (1%) | 100/598 f (16.7%) | N/A | N/A | N/A | N/A | 380/587 f (64.7%) |
| Matar c (2020) 48 | 136 | N/A | 1 (11.1%; 95% CI 6.3%–18.7%) | N/A | 2 | 31/94 (37.7%; 95% CI 26.9%–50.0%) | 5 | 8 | (76.3%; 95% CI 65.8%–84.2%) |
| Melo (2020) 49 | 60 f | 60 | N/A | N/A | N/A | 10/60 | N/A | N/A | 31 |
| Mirbeyk (2020) 50 | 386 | 299 | 2/386 (0.5%) | N/A | 10 (2.8%) | 65/276 (23.6%) | N/A | N/A | 257/299 (86.0%) |
| Muhidin (2020) 51 | 89 | 86 | 0 | 2 | 2 | 30 | N/A | 6 | 79/86 (91.9%) |
| Mullins (2020) 7 | 32 | 29 | 0/32 (0%) | N/A | N/A | 15/32 (46.9%) | N/A | N/A | 27/29 (93%) |
| Parazzini c (2020) 52 | 71 | 64 | N/A | 2/31 (6.5%; 95% CI 0.8%–2.4%) | N/A | 19/48 (39.6%; 95% CI 25.8%–54.7%) | N/A | N/A | 58 |
| Paulino Vigil‐De Gracia (2020) 53 | 83 | N/A | 0/83 (0%) | N/A | 3/83 (3.6%) | 4 | N/A | (9.6%) | (89%) |
| Pettirosso (2020) 54 | 1287 | 1002 | 8 | N/A | N/A | N/A | N/A | N/A | N/A |
| Rodríguez‐Blanco (2020) 55 | 79 | N/A | 0/79 (0%) | 3/70 (4.3%) | 3/70 (4.3%) | N/A | N/A | 9/74 (12.2%) | 65/73 (89.0%) |
| Sepúlveda‐Martinez c (2020) 68 | 292 | 251 | 0/292 (0%) | N/A | 3/292 (2%; 95% CI 1%–4%) | N/A | N/A | N/A | 176/220 (79%; 95% CI 69%–88%) |
| Sharps (2020) 56 | 325 | N/A | N/A | N/A | N/A | 58/225 (25.8%) | N/A | 9 (2.5%) | 83 (58%) |
| Simões (2020) 57 | N/A | N/A | 0 | N/A | N/A | N/A | N/A | N/A | N/A |
| Smith (2020) 58 | 92 | N/A | 0 | 1/23 (4.3%) | 1/23 (4.3%) | 6/13 (46%) | N/A | N/A | 40/50 (80%) |
| Soheili c (2020) 59 | 177 | N/A | 0 | 2 | 1 | 43/151 (28%; 95% CI 12%–44%) g | N/A | 11 | /94 (86%; 95% CI 75%–95%) |
| Sun c (2020) 60 | 41 | N/A | 0/41 (0%) | 2/41 (4.9%) | 2/41 (4.9%) | 17/41 (46%; 95% CI 30%–60%) | N/A | 3 (14%; 95% CI 3%–26%) | 33 (91.7%) |
| Teles Abrao (2020) 61 | 155 | 116 | N/A | 5/155 (3.2%) | N/A | 20/118 (17%) h | N/A | 10/116 (8.6%) | 107/116 (92.2%) |
| Trippella (2020) 62 | 275 | 239 | 1/275 (0.4%) | 10/275 (3.6%) | 5/275 (2%) | 48/208 (23%) | N/A | 24/275 (8.7%) | 179/239 (74.9%) |
| Trocado (2020) 63 | 95 | 50 | N/A | N/A | N/A | 18/51 (35.3%) | N/A | 5 (5%) | 47/50 (94%) |
| Turan (2020) 64 | 637 | 485 | 10/637 (1.6%) | 61/637 (9.6%) | 51/637 (8.0%) | 161/479 (33.6%) | 48/119 (40.3%) | 8 | 403/485 (83%) |
| Yang (2020) A 9 | 114 | 98 | N/A | N/A | N/A | (21.3%) | N/A | N/A | 89/98 (90.8%) |
| Yang (2020) B 65 | N/A | 83 | N/A | N/A | N/A | N/A | N/A | N/A | 73/83 (88%) |
| Yee c (2020) 69 | 93 | N/A | N/A | N/A | N/A | 17/68 (29.4%; 95% CI 9.6%–53.6%) | N/A | 9/71 (11.7%; 95% CI 4.5%–21.1%) | N/A |
| Yoon (2020) 66 | 223 | 201 | N/A | 5/223 (2.2%) | 5/223 (2.2%) | 48/185 (25.9%) g | N/A | 16/126 (12.7%) | 163/185 (88.1%) |
| Zaigham (2020) 67 | 108 | 86 | 0/108 (0%) | 3/108 (3%) | N/A | 20/48 (42%) | N/A | N/A | 79/86 (92%) |
Abbreviation: N/A, not available.
a
Pregnant women infected with SARS‐CoV‐2.
b
n, n/N (%) or (%; 95% CI) from meta‐analyses (fixed or random effect), according to the availability of data in the included systematic reviews.
c
Some outcomes were estimated from meta‐analyses using fixed or random effects.
d
Data from consecutive case series are presented, as the author of the review used these data to combine results from primary studies.
e
Data from case reports are presented separately for this outcome.
f
Inconsistency between tables and text, or within the manuscript for this outcome.
g
Weeks were not specified.
h
Nineteen women delivered between 32 and 36 weeks, and one before 32 weeks.