FIGURE 2.

Schematic diagram of the main expression of ACE2 in the whole body. ACE2 is expressed in the circumventricular organs of the CNS, upper respiratory tract (goblet and ciliated epithelial cells), the vascular system (endothelial cells, migratory angiogenic cells, and vascular smooth muscle cells), alveolar Type II epithelial cells of the lungs, and pulmonary vasculature, the liver (cholangiocytes and hepatocytes), enterocytes of the gut, kidneys (glomerular endothelial cells, podocytes, and proximal tubule epithelial cells), heart (cardiofibroblasts, cardiomyocytes, endothelial cells, pericytes, and epicardial adipose cells), eyes (pigmented epithelial cells, rod, and cone photoreceptor cells and Müller glial cells)