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Inhibiting STAT5 did not affect body weight or hyperlipidemia profile in HFD-fed ApoE-/- mice. (A) Western blotting showed that p-STAT5 level in artery tissues of ApoE-/- mice induced by HFD was decreased by STAT5-IN-1. (B-E) STAT5-IN-1 failed to alter HFD-induced body weight changes (B) and serum lipid levels (C-F). (n=12 in each group; ns, no significance, vs. HFD).
