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The effect of Nrf-2 on the level of CCL2, IL-1β, TNF-α, AT1R and ROS in placental tissue. A. The expression of CCL2, IL-1β, TNF-α, and AT1R of placental tissue in different groups were examined by western blot. B. The level of ROS in placental tissue was detected using ELISA kits. n=8, *P<0.05, **P<0.01 and ***P<0.001 vs. Control; #P<0.05 and ###p<0.001 vs. PE. ROS, Reactive oxygen species; CDDO-Im, Nrf-2 agonist; ML385, Nrf-2 inhibitor.
