Table 3.

Nonlinearity addressed through two‐piecewise linear model

Model	HR, 95% CI, p value
Fitting model by standardized Cox regression	2.14 (1.12, 4.08) 0.020
Fitting model by two‐piecewise linear model
Inflection point of log2 bNC	0.58, 1.83
≤0.58	0.19 (0.05, 0.66) 0.0094
>0.58 to ≤1.83	13.64 (0.25, 749.71) 0.2011
>1.83	2.82 (1.19, 6.67) 0.0186
Log likelihood ratio test	0.030

Note: The adjustment strategy was the same as fully adjusted model.

Abbreviations: bNC, baseline neutrophil count; CI, confidence interval; HR, hazard ratio.