Table 3.
Variables |
Death or mechanical ventilation (n = 13) |
No death nor mechanical ventilation (n = 27) |
P‐value |
---|---|---|---|
Age, years | 55.8 ± 11.2 | 53.2 ± 16.7 | 0.97 |
Male sex | 11 (84.6%) | 15 (55.6%) | 0.15 |
Blood type O (vs. other blood types) | 4 (30.8%) | 10 (37.0%) | 0.73 |
Blood type A (vs. other blood types) | 7 (53.8%) | 9 (33.3%) | 0.21 |
Pretransplant ischaemic cardiomyopathy | 5 (38.5%) | 6 (22.2%) | 0.28 |
Time post‐transplantation, years | 4.3 (1.4–8.8) | 5.0 (1.9–9.0) | 0.65 |
History of acute rejection | 8 (61.5%) | 17 (63.0%) | 0.99 |
History of ISHLT cardiac allograft vasculopathy 2 or 3 | 2 (15.4%) | 7 (25.9%) | 0.69 |
Cytomegalovirus positive status | 10/12 (83.3%) | 16/26 (61.5%) | 0.28 |
Epstein Barr Virus positive status | 12/12 (100.0%) | 23/25 (92%) | 0.99 |
Chronic kidney disease stage III or higher | 9 (69.2%) | 12 (44.4%) | 0.31 |
Diabetes mellitus | 7 (53.8%) | 9 (33.3%) | 0.25 |
Dyslipidaemia | 5 (38.5%) | 7 (25.9%) | 0.46 |
Hypertension | 9 (69.2%) | 19 (70.3%) | 0.99 |
Body mass index, kg/m2 | 26.3 ± 4.3 | 27.3 ± 6.2 | 0.60 |
Baseline medication | |||
ACE‐I or ARB | 7 (53.8%) | 9 (33.3%) | 0.25 |
Prednisone dosage >5 mg per day | 6 (46.2%) | 12 (44.4%) | 0.99 |
Dual immunosuppressive therapy | 1 (7.7%) | 4 (14.8%) | 0.65 |
CT lung involvement ≥50% | 8/12 (66.7%) | 3/21 (14.3%) | 0.006 |
Laboratory variables at admission | |||
Creatinine, µmol/l | 298.0 (149.0–522.0) | 137.0 (97.5–236.5) | 0.07 |
C‐reactive protein, mg/l | 75.5 (44.3–182.5) | 31.9 (3.0–62.6) | 0.01 |
NT‐proBNP, ng/l | 895.0 (429.8–3555.0) | 1084.0 (433.5–5847.0) | 0.89 |
White blood cell count, 109/l | 6.8 (4.8–11.3) | 5.7 (4.0–7.0) | 0.16 |
Lymphocyte count, 109/l | 0.53 (0.30–0.84) | 0.72 (0.43–1.02) | 0.23 |
Procalcitonin, µg/l | 0.80 (0.33–1.00) | 0.11 (0.04–0.72) | 0.054 |
Fibrinogen, g/l | 5.1 (3.4–7.8) | 4.9 (3.8–6.1) | 0.82 |
D‐dimer, ng/ml | 1524.0 (1268.0–5308.0) | 1156 (340.0–2151.0) | 0.22 |
ISHLT, International Society for Heart and Lung Transplantation.