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. 2021 Mar 5;34(4):721–731. doi: 10.1111/tri.13837

Table 3.

Markers of risk of death or need for mechanical ventilation.

Variables

Death or mechanical ventilation

(n = 13)

No death nor mechanical ventilation

(n = 27)

P‐value
Age, years 55.8 ± 11.2 53.2 ± 16.7 0.97
Male sex 11 (84.6%) 15 (55.6%) 0.15
Blood type O (vs. other blood types) 4 (30.8%) 10 (37.0%) 0.73
Blood type A (vs. other blood types) 7 (53.8%) 9 (33.3%) 0.21
Pretransplant ischaemic cardiomyopathy 5 (38.5%) 6 (22.2%) 0.28
Time post‐transplantation, years 4.3 (1.4–8.8) 5.0 (1.9–9.0) 0.65
History of acute rejection 8 (61.5%) 17 (63.0%) 0.99
History of ISHLT cardiac allograft vasculopathy 2 or 3 2 (15.4%) 7 (25.9%) 0.69
Cytomegalovirus positive status 10/12 (83.3%) 16/26 (61.5%) 0.28
Epstein Barr Virus positive status 12/12 (100.0%) 23/25 (92%) 0.99
Chronic kidney disease stage III or higher 9 (69.2%) 12 (44.4%) 0.31
Diabetes mellitus 7 (53.8%) 9 (33.3%) 0.25
Dyslipidaemia 5 (38.5%) 7 (25.9%) 0.46
Hypertension 9 (69.2%) 19 (70.3%) 0.99
Body mass index, kg/m2 26.3 ± 4.3 27.3 ± 6.2 0.60
Baseline medication
ACE‐I or ARB 7 (53.8%) 9 (33.3%) 0.25
Prednisone dosage >5 mg per day 6 (46.2%) 12 (44.4%) 0.99
Dual immunosuppressive therapy 1 (7.7%) 4 (14.8%) 0.65
CT lung involvement ≥50% 8/12 (66.7%) 3/21 (14.3%) 0.006
Laboratory variables at admission
Creatinine, µmol/l 298.0 (149.0–522.0) 137.0 (97.5–236.5) 0.07
C‐reactive protein, mg/l 75.5 (44.3–182.5) 31.9 (3.0–62.6) 0.01
NT‐proBNP, ng/l 895.0 (429.8–3555.0) 1084.0 (433.5–5847.0) 0.89
White blood cell count, 109/l 6.8 (4.8–11.3) 5.7 (4.0–7.0) 0.16
Lymphocyte count, 109/l 0.53 (0.30–0.84) 0.72 (0.43–1.02) 0.23
Procalcitonin, µg/l 0.80 (0.33–1.00) 0.11 (0.04–0.72) 0.054
Fibrinogen, g/l 5.1 (3.4–7.8) 4.9 (3.8–6.1) 0.82
D‐dimer, ng/ml 1524.0 (1268.0–5308.0) 1156 (340.0–2151.0) 0.22

ISHLT, International Society for Heart and Lung Transplantation.