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. 2021 Mar 2;51(6):1412–1422. doi: 10.1002/eji.202049072

Figure 2.

Figure 2

Reactivity of human IgG against rabbit, pig, and CMAH/GGTA1 DKO pig IgG. Serum from healthy volunteers (n = 59; 100‐fold dilutions) was incubated on ELISA plates coated with WT pig IgG, GGTA1 KO pig IgG, CMAH/GGTA1 DKO pig IgG, or rabbit IgG. Binding of human IgG was revealed with a labeled secondary antibody against human IgG. Symbols represent individual sera, and error bar represents mean ± SEM. Data are from three independent experiments. Nonparametric statistics were used for pairwise comparisons using Kruskal–Wallis tests. NS: not significant. ***p < 0.001.