Table II.
Comparison of clinical data of patients with different levels of COPD.
Parameters | Stable stage of COPD (n=44) | AECOPD (n=36) | P-value |
---|---|---|---|
Sex (male/female) | 23/21 | 25/11 | 0.119 |
Age (years) | 61.32±7.25 | 62.22±7.30 | 0.583 |
BMI | 23.42±1.41 | 23.17±1.56 | 0.454 |
Smoking index | 14.69±15.86 | 15.73±17.63 | 0.782 |
SO2 | 96.80±1.47 | 97.01±1.35 | 0.512 |
TG (mmol/l) | 1.41±0.72 | 1.16±0.57 | 0.094 |
TC (mmol/l) | 4.60±0.91 | 4.81±0.81 | 0.284 |
HDL (mmol/l) | 1.44±0.46 | 1.35±0.52 | 0.414 |
LDL (mmol/l) | 2.61±0.70 | 2.35±0.81 | 0.128 |
FEV1% predicted | 86.54±17.46 | 78.13±15.04 | 0.025 |
FEV1/FVC% | 61.63±9.58 | 56.03±8.93 | 0.009 |
TNF-α (pg/ml) | 2.94±2.01 | 2.20±1.80 | 0.090 |
CRP (µg/ml) | 22.56±16.86 | 24.24±15.77 | 0.649 |
MDA (µmol/l) | 4.11±1.90 | 4.73±1.98 | 0.158 |
SOD (U/ml) | 78.97±7.48 | 80.87±8.80 | 0.300 |
GSH (mg/l) | 304.43±31.96 | 276.47±38.71 | 0.001 |
COPD, chronic obstructive pulmonary disease; AE, acute exacerbation; BMI, body mass index; SO2, oxygen saturation; TG, triglyceride; TC, total cholesterol; HDL, high-density lipoprotein; LDL, low density lipoprotein; FEV1, forced expiratory volume in one second; FVC, forced vital capacity; TNF, tumor necrosis factor; CRP, C-reactive protein; MDA, malondialdehyde; SOD, superoxide dismutase; GSH, glutathione.