Table 1.
Select Figure of Merits Including the Method Detection Limits (MDLs), Limits of Detection (LODs), Limits of Quantification (LOQs), and Repeatability
| analytes | MDL (ng/L) | 95% confidence interval (ng/L) | LOD (ng/L) | LOQ(ng/L) | intraday precision (n = 9)a | interday precision (n = 9)a |
|---|---|---|---|---|---|---|
| Synthetic Opioids/Analgesics carfentanil | 1.00 | 0.70–2.30 | 0.50 | 1.50 | 0.71 | 1.16 |
| furanyl fentanyl | 1.50 | 1.00–3.30 | 0.90 | 3.20 | 0.30 | 0.76 |
| valeryl fentanyl | 1.00 | 0.70–2.20 | 0.10 | 0.20 | 0.50 | 0.58 |
| butyryl fentanyl | 1.10 | 0.70–2.50 | 0.30 | 0.90 | 0.68 | 0.85 |
| acetyl fentanyl | 0.70 | 0.50–1.60 | 0.10 | 0.40 | 0.36 | 0.92 |
| cyclopropyl fentanyl | 0.90 | 0.60–2.00 | 0.20 | 0.70 | 0.60 | 0.70 |
| benzyl fentanyl | 0.90 | 0.60–2.00 | 0.10 | 0.50 | 0.65 | 1.10 |
| 3′-methyl fentanyl | 1.30 | 0.80–2.90 | 0.10 | 0.30 | 0.53 | 0.48 |
| 4′-methyl acetyl fentanyl | 0.80 | 0.50–1.70 | 0.10 | 0.20 | 0.73 | 0.67 |
| 4-fluoro-isobutyryl fentanyl | 1.30 | 0.80–2.80 | 0.10 | 0.0.20 | 2.19 | 0.32 |
| para-fluorobutyryl fentanyl | 0.70 | 0.50–1.60 | 6.60 | 22.0 | 1.14 | 0.61 |
| methoxyacetyl fentanyl | 0.70 | 0.40–1.50 | 0.10 | 0.20 | 0.58 | 0.73 |
| 4-ANPP | 1.30 | 0.90–3.00 | 0.40 | 1.20 | 0.66 | 1.22 |
| U-48800 | 1.20 | 0.80–2.60 | 0.10 | 0.30 | 0.69 | 1.10 |
| U-47700 | 1.00 | 0.60–2.20 | 0.30 | 1.00 | 0.44 | 0.67 |
| Synthetic Cannabinoids | ||||||
| 5-fluoro MDMB-PICA | 1.00 | 0.60–2.20 | 0.20 | 0.70 | 0.94 | 2.57 |
| MAB-CHMINACA | 1.80 | 1.10–3.90 | 6.30 | 21.0 | 4.19 | 3.29 |
| MMB-FUBINACA | 2.90 | 1.90–6.40 | 0.80 | 2.60 | 1.56 | 2.33 |
| 5-fluoro EDMB-PINACA | 2.30 | 1.50–5.10 | 0.10 | 0.40 | 1.98 | 2.93 |
| (R)-5-fluoro ADB | 1.10 | 0.70–2.40 | 0.40 | 1.20 | 1.60 | 1.09 |
| AB-FUBINACA | 0.90 | 0.60–1.90 | 2.20 | 7.30 | 2.09 | 1.62 |
| MMB-CHMICA | 0.50 | 0.30–1.10 | 0.20 | 0.60 | 0.66 | 1.47 |
| AB-CHMINACA | 1.70 | 1.10–3.80 | 1.30 | 4.20 | 2.04 | 2.02 |
| ADB-FUBINACA | 0.90 | 0.50–1.90 | 1.0. | 3.50 | 3.32 | 1.41 |
| 5-fluoro AMB | 0.80 | 0.50–1.70 | 0.20 | 0.50 | 1.05 | 1.38 |
| NM2201 | 2.80 | 1.80–6.20 | 0.40 | 1.30 | 1.37 | 2.98 |
| Synthetic Cathinones | ||||||
| methcathinone | 1.20 | 0.80–2.70 | 0.70 | 2.20 | 0.97 | 0.99 |
| ethylone | 1.0. | 0.70–2.30 | 0.30 | 1.00 | 0.33 | 0.67 |
| 4-MMC (mephedrone) | 1.60 | 1.10–3.60 | 1.00 | 3.30 | 0.78 | 3.15 |
| 4-methyl pentedrone | 1.60 | 1.00–3.60 | 2.40 | 7.80 | 1.73 | 2.04 |
| N-ethylpentylone | 1.70 | 1.10–3.70 | 2.30 | 7.70 | 0.38 | 0.81 |
| α-pyrrolidinopropiophenone | 1.50 | 1.00–3.30 | 0.50 | 1.50 | 0.40 | 1.40 |
| 3,4-methylenedioxypyrovalerone | 0.90 | 0.60–2.10 | 0.40 | 1.40 | 0.45 | 0.76 |
| α-ethylaminohexanophenone | 1.40 | 0.90–3.20 | 2.50 | 8.40 | 0.61 | 2.53 |
| 2-methyl-4′-(methylthio)-2-morpholinopropiophenone | 0.60 | 0.40–1.30 | 0.20 | 0.80 | 0.40 | 1.52 |
| 4-chloro-α-PVP | 1.30 | 0.90–2.90 | 0.40 | 1.30 | 0.56 | 1.27 |
| Piperazines | ||||||
| 1-(3-chlorophenyl) piperazine (mCPP) | 2.20 | 1.40–4.80 | 0.90 | 2.90 | 1.93 | 1.80 |
| 1-cyclohexyl-4-(1,2-diphenylethyl) piperazine (MT-45) | 0.80 | 0.50–1.90 | 0.10 | 0.30 | 0.59 | 0.65 |
| Indole | ||||||
| 5-(2-aminopropyl) Indole (5IT) | 3.30 | 2.10–7.20 | 3.30 | 10.9 | 1.32 | 7.31 |
| Amphetamine | ||||||
| 4-methylamphetamine | 6.30 | 4.10–13.9 | 1.70 | 5.50 | 0.67 | 3.38 |
| Anticonvulsants | ||||||
| clonazepam | 3.40 | 2.20–7.50 | 1.90 | 6.30 | 0.78 | 1.61 |
| gabapentin | 248 | 159–546 | 3.40 | 11.2 | 1.64 | 2.45 |
a
Relative standard errors (±).