Skip to main content
. 2021 Mar 22;21(5):515. doi: 10.3892/etm.2021.9946

Figure 1.

Figure 1

Expression levels of MMPs and histone acetylation-associated factors (H4K5ac and H4K8ac) in fetal membrane tissues. Fetal membranes were divided into three groups (FTL, TPROM and PPROM), and levels of (A) MMP2 and MMP9, and (B) HDAC1, HDAC2 and HDAC6 were detected using ELISA kits. (C) Western blotting was performed to assess the protein levels of H4K5ac and H4K8ac in FTL, TPROM and PPROM groups. H4 served as an internal control. Data are expressed as mean ± standard deviation from three independent experiments. *P<0.05 and **P<0.01 vs. the FTL group. #P<0.05 vs. the TPROM group. MMPs, matrix metalloproteinases; H4K, histone H4 lysine; FTL, full-term labor; PROM, premature rupture of membranes; TPROM, term-PROM; PPROM, pre-term-PROM; HDAC, histone deacetylase; ac, acetylated.