Fig. 4.

Analysis of functional enrichment and protein levels of differentially abundant proteins.A, GO molecular function analysis of proteins only present in Baseline (at day of intubation). B, GO molecular function analysis of downregulated proteins in pre-VAP and VAP positive relative to Baseline. C, Median log2(FC) of protein abundance for 21 significant proteins in pre-VAP (dark red), VAP positive (red), and post-VAP (blue) compared with Baseline. D, Measurement of MPO and ELANE levels in VAP patients using MS aided relative abundance, log2(AUC) (left) and ELISA (ng/ml of ETA) (right).