Table III.
Comparison of ETA proteins between Baselines (from control and VAP patients) and VAP positive
| Protein Name | Gene ID | log2(FC)a | p Value | Median Area under Curve (AUC) |
||
|---|---|---|---|---|---|---|
| Control Baseline | VAP Patients |
|||||
| Baseline | VAP Positive | |||||
| Retinal dehydrogenase 1 | ALDH1A1 | −28.68 | 0.006 | 26.96 | 28.68 | 0.00 |
| Retinol-binding protein 4 | RBP4 | −27.42 | 0.014 | 28.44 | 27.42 | 0.00 |
| Tetranectin | CLEC3B | −27.06 | 0.009 | 25.23 | 27.06 | 0.00 |
| Isoform 2 of Keratin, type II cytoskeletal 8 | KRT8 | −29.58 | 0.009 | 27.59 | 29.58 | 0.00 |
| Gelsolin | GSN | −28.68 | 0.008 | 30.26 | 28.68 | 0.00 |
| Apolipoprotein A-IV | APOA4 | −26.16 | 0.013 | 25.07 | 26.16 | 0.00 |
| Pulmonary surfactant-associated protein B | SFTPB | −26.46 | 0.033 | 25.99 | 26.46 | 0.00 |
| Extracellular superoxide dismutase [Cu-Zn] | SOD3 | −24.88 | 0.009 | 24.53 | 24.88 | 0.00 |
| Keratin, type I cytoskeletal 19 | KRT19 | −27.95 | 0.001 | 27.81 | 27.95 | 0.00 |
| Tumor-associated calcium signal transducer 2 | TACSTD2 | −25.30 | 0.009 | 20.13 | 25.30 | 0.00 |
| x-ray repair cross-complementing protein 5 | XRCC5 | −24.52 | 0.025 | 21.24 | 24.52 | 0.00 |
| Keratin, type II cytoskeletal 5 | KRT5 | −27.25 | 0.008 | 25.77 | 27.25 | 0.00 |
| Fatty acid-binding protein, adipocyte | FABP4 | −27.70 | 0.009 | 28.34 | 27.70 | 0.00 |
| Folate receptor alpha | FOLR1 | −27.16 | 0.044 | 26.58 | 27.16 | 0.00 |
| Nucleolin | NCL | −26.60 | 0.024 | 24.80 | 26.60 | 0.00 |
| Peroxiredoxin-6 | PRDX6 | −26.31 | 0.009 | 25.34 | 26.31 | 0.00 |
| Flavin reductase (NADPH) | BLVRB | −26.14 | 0.009 | 25.21 | 26.14 | 0.00 |
| 14-3-3 protein beta/alpha | YWHAB | −28.61 | 0.003 | 27.98 | 28.61 | 0.00 |
| Heat shock 70 kDa protein 4 | HSPA4 | −25.93 | 0.002 | 25.93 | 25.93 | 0.00 |
| Hsc70-interacting protein | ST13 | −25.99 | 0.003 | 25.81 | 25.99 | 0.00 |
| Lumican | LUM | −27.13 | 0.024 | 25.53 | 27.13 | 0.00 |
| Tropomyosin alpha-4 chain | TPM4 | −25.46 | 0.019 | 26.43 | 25.46 | 0.00 |
| 14-3-3 protein eta | YWHAH | −27.34 | 0.032 | 26.10 | 27.34 | 0.00 |
| CD166 antigen | ALCAM | −26.52 | 0.006 | 26.37 | 26.52 | 0.00 |
| Glutamate-rich protein 3 | ERICH3 | −24.97 | 0.009 | 22.13 | 24.97 | 0.00 |
| Chloride intracellular channel protein 6 | CLIC6 | −26.08 | 0.008 | 25.22 | 26.08 | 0.00 |
| Peptidyl-prolyl cis-trans isomerase FKBP5 | FKBP5 | 1.71 | 0.032 | 0.00 | 23.39 | 25.10 |
| Ig kappa chain V-III region SIE | IGKV3-SIV | −2.56 | 0.044 | 0.00 | 28.12 | 25.57 |
| Ficolin-1 | FCN1 | 3.39 | 0.009 | 0.00 | 22.56 | 25.95 |
| Isoform 2 of Nucleoside diphosphate kinase A | NME1 | 26.56 | 0.029 | 0.00 | 0.00 | 26.56 |
| C-reactive protein | CRP | 28.11 | 0.037 | 0.00 | 0.00 | 28.11 |
a
Log2(FC) of VAP positive versus Baseline in VAP patients; p-value determined using Wilcoxon rank sum test.