Table III.
High confidence ClpXP substrates significantly enriched in CLPP-TRAP over CLPP-WT
| Gene names | TAILS | LFQ log2 (Clpp−/−/WT) | ANOVA q-value | log2 (TRAP/WT) | Peptides | Function |
|---|---|---|---|---|---|---|
| Clpx | No | 6.52 | 0.00 | 2.27 | 30 | Known Clp(X)P binding partners |
| Chchd2; Zbed5 | No | 1.18 | 0.00 | 2.98 | 5 | |
| Poldip2 | No | 2.53 | 0.00 | 3.66 | 18 | |
| Mrpl13 | No | n.d. | 0.00 | 3.20 | 6 | Mitochondrial Translation |
| Mrpl18 | Yes | n.d. | 0.01 | 3.65 | 2 | |
| Mrps22 | Yes | 1.18 | 0.02 | 3.35 | 6 | |
| Ndufv1 | Yes | −0.84 | 0.00 | 5.45 | 10 | Respiratory Chain |
| Uqcrc1 | Yes | −0.13 | 0.00 | 8.04 | 16 | |
| Ccrn4l | No | n.d. | 0.01 | 5.27 | 9 | Metabolism |