Table IV.
Putative ClpXP substrates and interactors significantly enriched in CLPP-TRAP over NEG
| Gene names | TAILS | ANOVA q-value | log2 (TRAP/NEG) | log2 (WT/NEG) | Peptides | Function |
|---|---|---|---|---|---|---|
| Clpp | No | 0.00 | 11.65 | 11.52 | 11 | Known Clp(X)P binding partners |
| C1qbp | No | 0.00 | 4.95 | 3.10 | 5 | |
| Mrpl12 | No | 0.01 | 1.23 | 0.94 | 3 | Mitochondrial Translation |
| Mrpl39 | Yes | 0.02 | 2.31 | 0 | 4 | |
| Atp5a1 | Yes | 0.02 | 1.06 | 0.93 | 14 | Respiratory Chain |
| Atp5b | Yes | 0.02 | 1.44 | 0.89 | 12 | |
| Atp5h;Gm10250 | Yes | 0.00 | 3.27 | 3.30 | 4 | |
| Tyms | No | 0.01 | 1.36 | 1.43 | 13 | Metabolism |
| Mthfd1l | No | 0.00 | 1.23 | 0.97 | 46 | |
| Fpgs | No | 0.03 | 3.38 | 0 | 3 | |
| Gstp1 | No | 0.03 | 1.63 | 0.80 | 3 | |
| Slc25a3 | Yes | 0.04 | 1.04 | 0.76 | 3 | Other |
| Usp15 | No | 0.01 | 1.26 | 0.60 | 8 | |
| Phb2 | No | 0.00 | 1.18 | 0.88 | 11 |