Table II.
Phosphorylated kinases and phosphatases
| Gene | Residue | NetworKIN Prediction | Class | Direction | Cell Wall Strength | MF Plates | MF Flask |
|---|---|---|---|---|---|---|---|
| Kinases | |||||||
| BckA | S 719 | MpkA | I | Down | NA | NA | NA |
| S 1003 | MpkA | II | Down | ||||
| ChkC | S 587 | MpkA | I | Down | + | + | NA |
| CmkC | S 34 | N/A | I | Up-Down | + | + | NA |
| S 475 | CmkC | II | Down | ||||
| Hk-8–4 | S 314 | Ste20 | I | Down | - | + | + |
| Kin1 | S 257 | Kin1 | II | Down | - | + | NA |
| MkkA | S 169 | PkcA | II | Down | NA | NA | NA |
| NimX | Y 15 | N/A | I | Down | NA | NA | NA |
| NpkA | S 74 | Snf1 | II | Down | - | + | NA |
| Nrc2 | S 433 | Nrc2 | II | Down | - | - | NA |
| PfkA | S 789 | PkaB | II | Down | NA | NA | NA |
| T 786 | N/A | II | Down | ||||
| PkiA | S 525 | PkcA | I | Down | NA | NA | NA |
| PkcB | S 633 | PkcB | I | Down | NA | NA | NA |
| PrkA | S 957 | N/A | I | Down | - | - | - |
| SchA | S 827 | TorA | I | Down | + | + | NA |
| S 298 | PhoA | I | Down | ||||
| S 285 | SrrB | II | Down | ||||
| SidB | S 453 | N/A | I | Up-Down | NA | NA | NA |
| S 44 | MpkA | I | Down | ||||
| S 47 | N/A | I | Up-Down | ||||
| SrrB | S 641 | PkaB | II | Down | - | + | NA |
| SteD | S 11 | Cka1 | II | Down | NA | NA | NA |
| Stk19 | S 875 | N/A | I | Up-Down | - | + | - |
| Yak1 | Y 502 | N/A | I | Up-Down | + | - | NA |
| Phosphatases | |||||||
| PtcA | S 41 | MpkA | I | Down | NA | NA | NA |
| AN1358 | T 390 | HogA | I | Down | NA | NA | NA |
| PodH | S 818 | I | Down | NA | NA | NA | |
Last three column contain phenotype data, MF is micafungin. NA: not applicable because experiment was not run on that strain (usually because kinase is essential), −: statistically significantly lower value than the control strain, +: either the same as or slightly higher than the control strain.