Fig. 5.

PolySTest outperforms individual tests for the 2-species data set as Miss test adds significant proteins.A, ROC curves show that combined tests, mostly supplied by the Miss test, considerably increase the true positive rate. Filled circles correspond to an FDR of 0.01. B, Comparison of test performance on basis of sensitivity and confidence (FDR: 0.01). C, Higher concentrations of E. coli proteins in mixture leads to more false positives which however follow the trend of the mixture as confirmed by high correlations to the given ratios. The dashed line corresponds to the averaged log-ratios of all E. coli proteins. Red lines are proteins with correlation > 0.99.