Fig. 6.

Improved recognition of proteins from Striated Muscle Contraction Pathway (Wikipathways) when differentiating into muscle cells.A, Illustration of the pathway and all 27 quantified proteins (red). B, Comparison of the significantly changing proteins of the different statistical tests for an FDR threshold of 0.05. A filled box denotes a protein with FDR < 0.05. C, Unscaled abundance changes and calculated false discovery rates for the different comparisons (3 proteins with more than 50% missing values are not shown in this figure). D, Enrichment of differentially regulated pathway proteins versus all DRFs comparing PolySTest and LIMMA.