Table 4.
Clinical characteristics in PAH with low, intermediate and high risks
| Variables | Low risk (n = 28) |
Intermediate risk (n = 34) |
High risk (n = 13) |
|---|---|---|---|
| WHO class (> 1), n (%) | 25 (89 %) | 31 (91 %) | 13 (100 %) |
| 6MWD, m | 461 ± 68 | 403 ± 97* | 344 ± 103* |
| NT-proBNP, pg/ml | 140 (60, 308) | 605 (223, 1820)* | 3475 (1678, 7344)*# |
| Maximal RA area, cm2 | 17 ± 6 | 24 ± 7* | 42 ± 17*# |
| RA pressure, mmHg | 5.8 ± 2.8 | 6.1 ± 3.6 | 16.8 ± 8.4*# |
| Cardiac index, l/min/m2 | 3.6 ± 2.7 | 2.5 ± 1.0* | 2.1 ± 0.6* |
| RVEF, % | 50 ± 10 | 39 ± 13* | 32 ± 11* |
Data are presented as mean ± SD, median (IQR) or n (%)
6MWD six-minute walking distance, EF ejection fraction, NT-proBNP N-terminal pro-brain natriuretic peptide, RA right atrial, RV right ventricular, WHO World Health Organization
*Significant difference compared to low risk; #significant difference compared to intermediate risk