Table 3a.

Medication effects: Lithium: Post-hoc Independent Samples T Tests, comparing FA in White Matter regions in participants with BD taking Lithium (BD+Li) vs. participants with BD not taking SGAs (BD-Li)

White Matter Region	BD + Li Mean ± SE n = 9	BD – Li Mean ± SE n = 19	Original p-value	FDR p-value
Genu of corpus callosum (GCC)	0.75 ± 0.010	0.71 ± 0.006	0.013	0.052
Body of the Corpus Callosum (BBC)	0.74 ± 0.009	0.70 ± 0.009	0.013	0.052
Retrolenticular part of internal capsule L (RPIC_L)	0.63 ± 0.006	0.60 ± 0.008	0.051	0.103
Anterior corona radiata L (ACR_L)	0.55 ± 0.012	0.52 ± 0.010	0.120	0.192
Superior corona radiata R (SCR_R)	0.54 ± 0.016	0.52 ± 0.010	0.283	0.323
Superior corona radiata L (SCR_L)	0.57 ± 0.011	0.54 ± 0.009	0.039	0.103
Cingulum R (Cingulum_R)	0.37 ± 0.011	0.35 ± 0.008	0.351	0.351
Superior longitudinal fasciculus L (SLF_L)	0.56 ± 0.011	0.54 ± 0.008	0.169	0.226

Abbreviations: BD: bipolar disorder; SE: standard error; FDR: false discovery rate; WM: white matter; Li: lithium