Fig. 1.

Protein expression and activity of AEP in brains of SAMP8 and SAMR1 mice. a Western blotting bands of mature AEP in the hippocampus and cortex of 4-month-old SAMP8 mice and age-matched SAMR1 mice. b Activity of AEP in the whole brains of 4-month-old SAMP8 and SAMR1 mice. * P < 0.05, Student’s t-test, n = 5 per group. c Mature AEP in the hippocampus and cortex of 6-month-old SAMP8 mice and age-matched SAMR1 mice. d AEP activity in the whole brains of 6-month-old SAMP8 and SAMR1 mice. * P < 0.05, unpaired Student’s t-test, n = 5 per group