Skip to main content
. 2021 Mar 31;10:12. doi: 10.1186/s40035-021-00235-4

Fig. 3.

Fig. 3

Effect of δ-secretase inhibitor 11 treatment on memory function of mice. a, b The swimming speed and escape latency of mice over the 5-day acquisition training. Two-way ANOVA analysis revealed the time effect (F (2.922, 35.06) = 9.659, P < 0.001) and group effect (F (3, 12) = 7.355, P < 0.05) on escape latency. SAMP8 mice learned significantly slower than SAMR1 mice (P < 0.05), and the vehicle-treated SAMP8 mice learned significantly slower than the δ-secretase inhibitor 11-treated SAMP8 mice (P < 0.05). n = 9 mice per group. c, d The percentage of time spent and the distance travelled in the target quadrant in the probe test, which was performed on day 6. *P < 0.05, n = 9 mice per group, one-way ANOVA followed by a Tukey’s post-hoc test