(A)
Schematic illustration of the fabrication and therapeutic mechanism
of siRNA and DTX coloaded host–guest gold nanorods (GNRs).
(B) Temperature elevation, (C) infrared thermal images of 4T1 tumors
upon laser irradiation at various power densities (200, 300, 400,
and 500 mW cm –2), (D) tumor growth curves, and
(E) change of tumor weight after treated with GDTX/siRNA nanoparticles
and 655 nm laser; the black arrows indicated the time points for DTX/siRNA
injection and laser irradiation. (F) Tumor photographs with different
treatment. Reproduced from ref (248) with permission from Wiley.