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a) Inhibition of the [3H]5-HT uptake in human platelets by 20b, 20d, 21b, and 21d compounds. Platelets were incubated in duplicate with [3H]5-HT in the presence and absence of increasing concentrations of each compound as described in the Methods section. b) The Lineweaver–Burk plot showing competitive inhibition of the [3H]5-HT uptake by compound 20b and paroxetine.
