Figure 1. Ikaros family member-dependent transitions and expression patterns in developmental pathways for B cell, T cell, and ILC lineages.
Ikaros zinc finger transcription factors exhibit distinct expression patterns and regulatory roles throughout lymphopoiesis. Expression of each factor is indicated by a colored circle in the nucleus of relevant cell populations. Speculated/likely expression patterns are denoted by faded circles and dashed outer lines. Where known, developmental transitions that require individual factors are indicated by inclusion of those factors at the indicated transition point.