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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Depress Anxiety. 2019 Sep 2;36(11):1047–1057. doi: 10.1002/da.22952

Table 2.

Seed-to-voxel functional connectivity clusters at baseline associated with symptom improvement after treatment from Philip et al. (Philip et al., 2018).

Scale Seed-to-Cluster Pair Peak MNI Coordinate Cluster
Size
Cluster p-FDR

PCL L. Amygdala-L. MPFC −20 +54 +16 723 <.001
R. Amygdala-L. MPFC −14 +60 +10 363 <.001
R. Amygdala-VMPFC −16 +22 –8 226 <.001
R. sgACC-R. Lat. PFC 16 +2 +58 151 <.005
R. sgACC-L. Lat. PFC −20 +8 +54 143 <.005

IDSSR L. Amygdala-L. MPFC −22 +54 +16 349 <.001
L. Amygdala-L. DLPFC −26 +30 +46 60 <.001
R. Amygdala-L. MPFC −14 +62 –12 138 <.001

Abbreviations: MNI, Montreal neurological institute; FDR, false-discovery rate; L, left; R, right; MPFC, medial prefrontal cortex; PCL, PTSD checklist for DSM-5; IDSSR, inventory of depressive symptomatology, self-report; DLPFC, dorsolateral prefrontal cortex; VMPFC, ventromedial prefrontal cortex; Lat, lateral; PFC, prefrontal cortex