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. 2020 Oct;25(5):416–420. doi: 10.17712/nsj.2020.5.20200026

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Histopathological examination of the lesion a) Smear preparation showing bipolar cells (arrows) with long processes reminiscent of pilocytic astrocytoma (Hematoxylin and Eosin, x200). b) A low magnification image showing the neoplastic bipolar cells with their distinct angiocentric arrangement which is mostly parallel in this tumor (arrows). (Hematoxylin and Eosin, x100). c) The myxoid component is very hypocellular but retains the angiocentric pattern(arrows). (Hematoxylin and Eosin, x100). d) GFAP is diffusely expressed in tumor cells (arrows) and particularly highlights the angiocentric pattern (GFAP, polyclonal, Ventana, x200). e) D2-40 is strongly expressed (arrows), (clone D2-4, DakoCytomation, x400). f) EMA showing moderate staining of cells and their processes. Note the perinuclear accentuation of expression in some cells (arrows), (EMA, clone E29, Dako x400).